Lauren Moissiy, MS, LCGC

The Genomics Edit

Should Healthy People Get Whole-Genome Sequencing?

Should Healthy People Get Whole-Genome Sequencing?

More information is not always more clarity. Here is what to consider before testing when you're healthy.

By Lauren Moissiy, MS, LCGC

Editorial draft for review. Research claims and sources require author verification before publication.

In this issue

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What the evidence shows

Editorial draft for review. Whole-genome sequencing examines much of your DNA, but it does not provide a complete forecast of your health. For a healthy person, the decision depends on family history, goals, and whether a finding would lead to an evidence-based change in care. A targeted test may sometimes be more appropriate. Testing may identify a medically relevant finding, an uncertain result, or no finding that explains your concern. A negative result does not erase risk, and uncertain findings should not be treated as proof of disease. Ask about secondary findings, privacy, cost, and possible follow-up testing. Speak with a qualified clinician or genetic counselor before testing. Choosing to wait until you have a clearer question can also be reasonable. Educational information only; not individualized medical advice.

What remains uncertain

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What this means for you

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Lauren’s take

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Sources and further reading

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© 2026 Lauren Moissiy, MS, LCGC